Dynamic endosomolytic polymer conjugates for pDNA und siRNA delivery
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چکیده
Diese Dissertation wurde selbständig, ohne unerlaubte Hilfe erarbeitet.
منابع مشابه
Breathing life into polycations: functionalization with pH-responsive endosomolytic peptides and polyethylene glycol enables siRNA delivery.
siRNA has been widely used to identify gene functions and holds great potential in providing a new class of therapeutics.1 The lack of efficient delivery systems is limiting the full therapeutic potential of siRNA technology and represents a challenging hurdle in this field of therapy. For the purpose of nucleic acid transfer, among other synthetic carrier systems, polycations have been applied...
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تاریخ انتشار 2009